Endocrine Abstracts

Background:.Quality of Life Assessment of Growth Hormone Deficiency in Adults (QoL-AGHDA) was designed for use in patients with GHD, a condition characterized amongst other things, by impairment in QoL. For use in cost-utility analysis outcomes should be measured on a scale of social preferences that assigns values of 1 and 0 to full health and dead. Condition-specific instruments may generate summary index scores but typically lack the legitimacy for use as measures of QoL ou...

Background: Although the negative impact of GHD in adults on quality of life (QoL) is well recognized and it has become routinely measured in clinical practice, there is still limited information about the extent of the differential between adults with GHD and their age/sex-matched peers within the general population.Objectives: The study was designed to test the discriminatory power of QoL-AGHDA by determining normative reference values in the general p...